What is PDGF+?

Platelet-Derived Growth Factor (PDGF) is one of the body’s most powerful natural healing proteins. It plays a critical role in tissue repair and regeneration by signaling fibroblasts and stem cells to produce new collagen, elastin, and new blood vessels. This cellular communication is essential for restoring skin strength, elasticity, and overall vitality.

Ariessence Pure PDGF+ is a next-generation, pharmaceutical-grade formulation designed to optimize these regenerative processes. Using advanced recombinant technology, PDGF is produced in a controlled, sterile laboratory environment—ensuring exceptional purity, potency, and consistency.

Unlike traditional PRF treatments, Ariessence Pure PDGF+ eliminates the need for blood draws. This offers a convenient, non-invasive alternative while delivering highly concentrated, purified growth factor therapy directly to areas needing rejuvenation.

How PDGF+ Works

PDGF stimulates:

• Increased collagen and elastin production
• Cellular proliferation and tissue remodeling
• New blood vessel formation
• Accelerated healing and repair

Research indicates that purified PDGF can be 100,000–300,000 times more potent than naturally occurring growth factor levels in the body, allowing for enhanced and targeted regenerative signaling.

When delivered through microneedling, PDGF+ initiates immediate bioactive signaling, promoting rapid repair and progressive skin improvement.

Patients often notice visible improvements within two weeks, with continued enhancement over several weeks as collagen remodeling progresses.

PDGF+ vs. PRF: Understanding the Difference

While PRF (Platelet-Rich Fibrin) utilizes a mixture of platelets, fibrin matrix, and white blood cells to gradually release growth factors over time, PDGF+ is a refined, purified growth factor therapy.

Key distinctions:

Source:
Ariessence PDGF+ is produced using recombinant technology in a sterile lab setting. PRF is derived from the patient’s blood.

Consistency:
PDGF+ delivers a standardized, predictable concentration. PRF results may vary depending on individual platelet counts.

Purity:
PDGF+ contains no human-derived components. PRF includes platelets and fibrin.

Potency:
PDGF+ provides a highly concentrated, bioactive formula designed for immediate targeted cellular signaling.

Both therapies are regenerative in nature; PDGF+ represents a next-generation, precision-based approach within regenerative aesthetics.

How PDGF+ is Paired with Microneedling

Microneedling creates controlled microchannels within the skin, stimulating the body’s natural wound-healing cascade and triggering collagen production. These microchannels also serve as precise delivery pathways for topical growth factor therapies.

When Ariessence Pure PDGF+ is applied during microneedling:

• The microchannels allow for enhanced penetration of PDGF+ into the dermis
• Immediate cellular signaling is initiated at the site of controlled injury
• Fibroblasts are stimulated to increase collagen and elastin production
• Tissue remodeling and vascular support are accelerated

Because PDGF is a key protein involved in wound healing and tissue repair, pairing it with microneedling amplifies the regenerative response beyond collagen induction alone.

This combination results in:

• Faster recovery compared to microneedling alone
• Enhanced collagen remodeling
• Improved skin firmness and elasticity
• More rapid improvement in texture and tone

By delivering purified, highly concentrated PDGF directly into the skin during the micro-injury phase, treatment outcomes are optimized through precision-based regenerative signaling.

Microneedling + PDGF+

$895 per session
(Add-on neck $175)

Package Options

3 Session Package – $2,550
($850 per session)

4 Session Package – $3,200
($800 per session)